Nos activités de recherche en laboratoire se concentrent sur les thématiques suivantes :

  • biologie

  • microbiologie

  • sciences de matériaux et chimie des polymères

Les connaissances acquises sont ensuite adaptées pour améliorer notre pratique en clinique. Vous trouverez ci-dessous des liens vers nos publications et des informations sur nos travaux présentés à l’international.

Presentations internationales



  • Shining a light on high volume photocurable materials. William Palin, Julian G. Leprince and Mohammed Hadis. Dent. Mater. 2018;34:695-710

  • Investigating the limits of resin-based luting composite photopolymerization through various thicknesses of indirect restorative materials. Chloé F. Hardy, Sabine Bebelman, Gaëtane Leloup, Mohammed Hadis, William Palin and Julian G. Leprince Dent. Mater. 2018

  • Composition of Dental Resin-Based Composites for Direct Restorations, Developing a More Appropriate Classification System for Modern Resin-Based Composite Technologies – Dental Composite Materials for Direct Restorations. Luc D. Randolph, Julian G. Leprince, William Palin. Edited by Vesna Miletic. Springer. 2018


  • Considerations for the Restoration of Endodontically Treated Molars – The Guidebook to Molar Endodontics. Julian G. Leprince, Chloé Hardy, Gaëtane Leloup. Edited by Ove A. Peters. Springer. 2017

  • Extracellular matrix-derived hydrogels for dental stem cells delivery. A. Viswanath, Julie Vanacker, L. Germain, Julian G Leprince, A. Diogenes, K.M. Shakesheff, L. White, Anne des Rieux. J of Bio Mater Research Part A. 2017;105:319-28


  • Filler characteristics of modern dental resin composites and their influence on physico-mechanical properties. Luc D. Randolph, William M. Palin, Gaëtane Leloup, Julian G. Leprince. Dent Mater. 2016;29

  • Efficient functionalization of alginate biomaterials. Dalheim MØ, Vanacker J, Najmi MA, Aachmann FL, Strand BL, Christensen BE. Biomaterials. 2016 Feb;80:146-56

  • Photopolymerization of highly filled dimethacrylate-based composites using Type I or Type II photoinitiators and varying co-monomer ratios. Randolph LD, Steinhaus J, Möginger B, Gallez B, Stansbury J, Palin WM, Leloup G, Leprince JG. Dent Mater. 2016 Feb;32(2):136-48

  • Bacterial adhesion mechanisms on dental implant surfaces and the influencing factors. A. Han, J.K.H. Tsoi, F.P. Rodrigues, Julian G. Leprince, William M. Palin. Int J Adhesion and Adhesives. 2016;69:58-71


  • Electrical enhancement of chlorhexidine efficacy against the periodontal pathogen Porphyromonas gingivalis within a biofilm. Lasserre JF, Leprince JG, Toma S, Brecx MC. New Microbiol. 2015;38(4):511-9

  • Dental Apical Papilla as Therapy for Spinal Cord Injury. De Berdt P, Vanacker J, Ucakar B, Elens L, Diogenes A, Leprince JG, Deumens R, des Rieux A. J Dent Res. 2015;94(11):1575-81

  • Tooth Retrospective Dosimetry Using Electron Paramagnetic Resonance: Influence of Irradiated Dental Composites. Desmet CM, Djurkin A, Dos Santos-Goncalvez AM, Dong R, Kmiec MM, Kobayashi K, Rychert K, Beun S, Leprince JG, Leloup G, Levêque P, Gallez B. PLoS One. 2015;10(6):e0131913

  • Temozolomide-loaded photopolymerizable PEG-DMA-based hydrogel for the treatment of glioblastoma. Fourniols T, Randolph LD, Staub A, Vanvarenberg K, Leprince JG, Préat V, des Rieux A, Danhier F. J Control Release. 2015;210:95-104

  • Fibrin hydrogels to deliver dental stem cells of the apical papilla for regenerative medicine. Germain L, De Berdt P, Vanacker J, Leprince J, Diogenes A, Jacobs D, Vandermeulen G, Bouzin C, Préat V, Dupont-Gillain C, des Rieux A. Regen Med. 2015;10(2):153-67


  • Influence of composition on setting kinetics of new injectable and/or fast setting tricalcium silicate cements. Setbon HM, Devaux J, Iserentant A, Leloup G, Leprince JG. Dent Mater. 2014;30(12):1291-303

  • The effect of ultra-fast photopolymerisation of experimental composites on shrinkage stress, network formation and pulpal temperature rise. Randolph LD, Palin WM, Watts DC, Genet M, Devaux J, Leloup G, Leprince JG. Dent Mater. 2014;30(11):1280-9

  • The type and composition of alginate and hyaluronic-based hydrogels influence the viability of stem cells of the apical papilla. Lambricht L, De Berdt P, Vanacker J, Leprince J, Diogenes A, Goldansaz H, Bouzin C, Préat V, Dupont-Gillain C, des Rieux A. Dent Mater. 2014;30(12):e349-61

  • PLGA nanoparticles loaded with host defense peptide LL37 promote wound healing. Chereddy KK, Her CH, Comune M, Moia C, Lopes A, Porporato PE, Vanacker J, Lam MC, Steinstraesser L, Sonveaux P, Zhu H, Ferreira LS, Vandermeulen G, Préat V. J Control Release. 2014;194:138-47

  • Hypoxia modulates the differentiation potential of stem cells of the apical papilla. Vanacker J, Viswanath A, De Berdt P, Everard A, Cani PD, Bouzin C, Feron O, Diogenes A, Leprince JG, des Rieux A. J Endod. 2014;40(9):1410-8

  • Physico-mechanical characteristics of commercially available bulk-fill composites. Leprince JG, Palin WM, Vanacker J, Sabbagh J, Devaux J, Leloup G. J Dent. 2014;42(8):993-1000

  • Ultra-fast light-curing resin composite with increased conversion and reduced monomer elution. Randolph LD, Palin WM, Bebelman S, Devaux J, Gallez B, Leloup G, Leprince JG. Dent Mater. 2014;30(5):594-604

  • Reduced polymerization stress of MAPO-containing resin composites with increased curing speed, degree of conversion and mechanical properties. Palin WM, Hadis MA, Leprince JG, Leloup G, Boland L, Fleming GJ, Krastl G, Watts DC. Dent Mater. 2014;30(5):507-16


  • Influence of free radicals signal from dental resins on the radio-induced signal in teeth in EPR retrospective dosimetry. Levêque P, Desmet C, Dos Santos-Goncalvez Ana M, Beun S, Leprince Julian G, Leloup Gaëtane, Gallez B. PLoS One. 2013;8(5):e62225

  • Progress in dimethacrylate-based dental composite technology and curing efficiency. Leprince JG, Palin WM, Hadis MA, Devaux J, Leloup G.  Dent Mater. 2013;29(2):139-56


  • Benefits and limitations of adding hyperbranched polymers to dental resins. Dewaele M, Leprince JG, Fallais I, Devaux J, Leloup G. J Dent Res. 2012;91(12):1178-83

  • Spectral spatial electron paramagnetic resonance imaging as a tool to study photoactive dimethacrylate-based dental resins. Levêque P, Leprince JG, Bebelman S, Devaux J, Leloup G, Gallez B.  J Magn Reson. 2012;220:45-53

  • Interactions between immune system and mesenchymal stem cells in dental pulp and periapical tissues. Leprince JG, Zeitlin BD, Tolar M, Peters OA. Int Endod J. 2012;45(8):689-701

  • New insight into the « depth of cure » of dimethacrylate-based dental composites. Leprince JG, Leveque P, Nysten B, Gallez B, Devaux J, Leloup G. Dent Mater. 2012;28(5):512-20

  • Physical, mechanical and rheological characterization of resin-based pit and fissure sealants compared to flowable resin composites. Beun S, Bailly C, Devaux J, Leloup G. Dent Mater. 2012;28(4):349-59


  • High irradiance curing and anomalies of exposure reciprocity law in resin-based materials. Hadis M, Leprince JG, Shortall AC, Devaux J, Leloup G, Palin WM.  J Dent. 2011;39(8):549-57

  • Photoinitiator type and applicability of exposure reciprocity law in filled and unfilled photoactive resins. Leprince JG, Hadis M, Shortall AC, Ferracane JL, Devaux J, Leloup G, Palin WM. Dent Mater. 2011;27(2):157-64


  • Irradiation modes’ impact on radical entrapment in photoactive resins. Leprince JG, Lamblin G, Devaux J, Dewaele M, Mestdagh M, Palin WM, Gallez B, Leloup G. J Dent Res. 2010;89(12):1494-8

  • Pulpal-temperature rise and polymerization efficiency of LED curing lights. Leprince J, Devaux J, Mullier T, Vreven J, Leloup G. Oper Dent. 2010;35(2):220-30

  • Hydroxyl radical release from dental resins: electron paramagnetic resonance evidence. Lamblin G, Leprince J, Devaux J, Mestdagh M, Gallez B, Leloup G. Acta Biomater. 2010;6(8):3193-8

  • Investigating filler morphology and mechanical properties of new low-shrinkage resin composite types. Leprince J, Palin WM, Mullier T, Devaux J, Vreven J, Leloup G. J Oral Rehabil. 2010 1;37(5):364-76